CDMO Solutions

Today, cell engineering is one of the most successful applications of ad- vanced medicine. Porton Advanced offers both autologous and allogeneic cell engineering platforms with integrated supports including

• CRO service
• cGMP manufacturing
• Process development
• Testing services
• Analytical development
• Regulatory assistance

As a carrier of target genes, plasmids have a significant impact on the quality, safety, and effectiveness of the gene and cell engineering final products. Our teams have years of proven experience in plasmid manufacturing, including:

• Construction Optimization
• GMP Manufacturing Process
• Colony Selection
• Analytical Development

Porton Advanced's proprietary HEK293TG2S cell line enables a high virus titer and is easy to scale up. We have also developed a unique purification technology that has high recovery rates, low residues, and high infectious titer.

mRNA is a promising and rapidly growing new type of advanced medicine with quick production speed, the ability to encode varied proteins, an excellent safety and efficacy profile, and flexibility in modality and formulation. We are able to provide end-to-end CRO and CDMO services.

Porton Advanced has well-trained and highly experienced teams that provide flexible process development support to suit the different needs of our clients.

A lentivirus is a single-strandedRNA retrovirus that is widely used as a gene transfer tool in cell and gene therapies based on its ability to infect both dividing cells and differentiated non-dividing cells.

Our Quality Management System (QMS) ensures that our quality system complies with FDA, EU and NMPA GMP requirement regarding material & supplier management, manufacturing management, data integrity, Good Documentation Practice(GDP)management, etc.

Our analytical teams at Porton Advanced Solutions have enriched experience in method development, verification, validations in a wide range of Advanced Therapy Medicinal Products(ATMPs).